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150例HIV感染者/AIDS病人HCV混合感染和CD4+T淋巴细胞变化分析

     

摘要

目的探讨HIV感染者/AIDS病人HCV混合感染率和CD4+T淋巴细胞变化情况。方法 收集我市疾控中心2011年1月~2012年10月检查的150例HIV感染者/AIDS病人,所有患者均进行HIV确证实验,经过确证后进行HCV检查和T淋巴细胞测定采用流式细胞仪检测。结果 150例均经确证实验确证为HIV-1抗体阳性,经过性传播77例,占32.0%,吸毒传播55例,占36.7,母婴传播2例,占1.3%,原因不明16例,占10.7%。抗-HCV阳性148例,抗-HCV阳性率为98.7%。150例HIV感染者/AIDS病人在初次检查时,CD4+T>500个/ mm3有44例,占29.3%,1年后只有21例仍然>500个/ mm3,初次检查CD4+T<200个/mm331例,1年后增加到35例,CD4+T细胞随着时间的推移逐步减少。结论 我市部分HIV感染者/AIDS病人疾病进展缓慢,必须加强监测掌握病情变化,对达到治疗标准的HIV感染者/AIDS病人应及时启动HAART治疗。%Objective: To investigate HIV infection / AIDS patients with HCV mixed infection and CD4+T changes. Methods: city CDC January 2010 to December 2011 examined 150 cases of HIV / AIDS patients, all patients were tested for HIV confirmation test after after diagnosis HCV checks and T lymphocytes was determined by streaming cytometric detection. Results: 150 cases were confirmed experiment confirmed HIV-1 antibody positive after sexually transmitted 77 cases, accounting for 32.0%, 55 cases of drug use spread, 36.7, mother-to-child transmission of the two cases, accounting for 1.3%, the unexplained 16 cases, accounting for 10.7%. 148 cases of anti-HCV positive anti-HCV positive rate was 98.7%. 150 cases of HIV infection / AIDS patients in the initial examination, CD4 + T> 500 Ge / mm3 with 44 cases, accounting for 29.3%, after one year, only 21 cases remained> 500 / mm3 initial inspection CD4 + T <200 Ge / mm3 31 Li, one year later increased to 35 cases, CD4+Tcells over time, gradually reduce. Conclusion: the city by HIV / AIDS patients in disease progression is slow, and the need to strengthen the monitoring master condition changes, to achieve the standard of care for HIV infection / AIDS patients should start HAART treatment in a timely manner.

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