评价室壁瘤患者左室整体和局部收缩与舒张功能受损情况

摘要

Purpose: To assess left ventricular (LV) global and regional function of systolic and diastolic in the patients with ventricular aneurysm after anterior wall myocardial infarction, we analyzed high - temporal - resolution LV global and regional time - activity curves obtained from gated radionuclide ventriculargraphy. Materials and Methods: The patients were divided into three groups, a control group(G0) of 15 normal peoples, and two groups of patients with previous anterior wall myocardial infarction, a first group(G1) of 29 patients without aneurysm, a second group(G2) of 15 patients with aneurysm. The parameters included:①LV global systolic and diastolic function parameters, ②LV regional systolic and diastolic function parameters. Results: ① LV global systolic function: the parameters of LVEF PER 1/3EF 1/3ER in G2 were reduced significantly than that in G0 and G1(P ＜ 0. 001). ②LV global diastolic function: the parameters of PFR 1/3FF 1/3FR in G2 were reduced significantly than that in G0 and G1 (P ＜ 0. 001) . ③LV regional systolic function: the parameter of LVREF in G2 were reduced significantly in all LV regional 6 segments than that in G0 and G1 (P ＜ 0.01) . ④LV regional distolic function: the parameter of LVRi/3FF in G2 were reduced significantly in all LV regional 6 segments than that in G0 and G1 (P ＜ 0.01). Conclusion: Forming of left ventricular aneurysm had produced damage on left ventricular global and regional function of systolic and diastolic.%目的:利用放射性核素心室造影技术评价前壁心肌梗死后室壁瘤形成对左心室整体和局部的收缩及舒张功能的影响.材料和方法:患者分为对照组(G0)15名,单纯前壁心肌梗死组(G1)29名,前壁心肌梗死并发室壁瘤组(G2)15名.运用放射性核素心室造影检查技术测定心功能指标:①左室整体收缩功能参数:LVEF、TPE、PER、1/3EF、1/3ER.②左室整体舒张功能参数:TPF、PFR、1/3FF、1/3FR.③左室局部收缩功能参数:LVREF(6个节段).④左室局部舒张功能参数:LVR1/3FF(6个节段).结果:①左室整体收缩功能参数,在LVEF、PER、1/3EF、1/3ER中,G2较G1和G0有明显下降(P＜0.001).②左室整体舒张功能参数,PFR、1/3FF、1/3FR,G2比G1和G0有明显下降(P＜0.001).③左室局部收缩功能参数,LVREF在所有1-6 节段G2较G1和G0有明显下降(P＜0.01).④左室舒张功能参数,LVR1/3FF在所有1-6 节段G2较G1和G0有明显下降(P＜0.01).结论:左心室壁瘤的形成对左心室整体和局部的收缩和舒张功能已经构成了严重的损害.