血栓对非瓣膜型房颤患者左心耳及相邻结构形态学影响的MSCT研究

摘要

Purpose:To analyze the effect of thrombi on the morphology changes of left atrial appendage and adjacent structures in patients with non-valvular atrial fibrillation,to provide accurate data to support further clinical treatment.Methods:Fourty-eight patients with non-valvular atrial fibrillation were enrolled,24 of them were with no thrombosis,24 of them were with thrombosis.The morphological changes of left atrial appendage and adjacent structures were retrospectively analyzed.Results:There were significant differences (P ＜0.05) of the length of left atrial appendage,short neck,perimeter and area,left atrial appendage volume and left atrial volume between patients with non-thromboembolic events and those with thrombosis,(P ＜0.05);There was no statistical significant difference of the length of the left atrial appendage,the shortest distance between the left atrial appendage opening and the mitral annulus.The length of the left atrial appendage (LAA) from the LSPV,left lower pulmonary vein (LIPV) length were with no statistical significant difference (P ＞0.05).Conclusion:MSCT coronary angiography can display the left atrial appendage objectively and accurately.The effects of thrombus formation on the morphology of left atrial appendage in patients with non-valvular atrial fibrillation can be demonstrated,and accurate data for the clinical further treatment can be provided.%目的:分析血栓对非瓣膜型房颤患者左心耳及相邻结构形态学影响,为临床的进一步治疗提供准确的数据支持.方法:搜集48例非瓣膜性房颤患者其中24例无血栓,24例有血栓形成,回顾性分析左心耳及相邻结构形态学改变特点.结果:无血栓事件发生非瓣膜型房颤患者组较有血栓病例组左心耳开口长径、短颈、周长、面积均有显著性差异(P＜0.05);左心耳容积、左心房容积及LSPV(左上肺静脉)口长径均有显著性差异(P＜0.05),左心耳主分叶长及左心耳第一个弯曲的角度均没有显著性差异(P＞0.05),左心耳脊的长度及左心耳开口到二尖瓣环之间的最短距离,LAA(左心耳)距LSPV、LIPV(左下肺静脉)长度均没有显著性差异(P＞0.05).结论:MSCT冠脉CTA成像能客观,准确地显示左心耳.观察非瓣膜性房颤患者有无血栓形成对左心耳形态学变化的影响,为临床的进一步治疗提供准确的数据支持.