高敏C反应蛋白和超敏肌钙蛋白T在不稳定型心绞痛患者危险分层中的临床应用

摘要

Objective To explore the application of hs CRP and TnT-hs for risk stratification of patients with unstable angina pectoris, in order to offer some guidance for the clinical practice application. Methods From Feburary 2011 to July 2012, The 170 patients with unstable angina accepted in our hospital. Within 1 day after admission, the hs-CRP of patients in blood and the TnT-hs level was detected. According to TnT-hs concentration level, they could be divided into negative group (108 cases) and the positive group (62 cases);before patients go through the standard therapy. Results The ECG and the negative group (0%), elevated ST segment 0 people, 47 (43.5%), ST segment and/or T wave inversion;positive group of three people (4.8%) in the elevated ST segment, 38 (61.3%), ST segment and/or T wave inversion. Conclusion Using the hs CRP, TnT-hs level for risk stratification in patients with unstable angina pectoris is crucial for unstable angina pectorisdiagnosis, treatment and prognosis of the disease. The application is worthy of clinical application.%目的：对高敏C反应蛋白(hs-CRP)、超敏肌钙蛋白T(TnT-hs)在不稳定型心绞痛患者危险分层中的临床效果进行探析,以期为临床实际中应用提供一定的指导。方法试验对象为本院于2011年2月~2012年7月收治的170例不稳定型心绞痛患者。在收治后的1 d内,对患者进行血液hs-CRP、TnT-hs水平的检测。根据TnT-hs浓度水平,将患者分为阴性组(108例)和阳性组(62例)两组,分别对患者行心电图(ECG)检测。规范治疗后,对各患者进行为期1年以上的随访,对患者可能发生的心血管病事件(如恶性心律失常、急性心肌梗死、猝死等)进行统计。结果行ECG后,阴性组中有0例(0)ST段升高,47例(43.5%)ST段下降和(或)T波倒置；阳性组中有3例(4.8%)ST段升高,38例(61.3%) ST段下降和(或)T波倒置。结论利用hs-CRP、TnT-hs水平对不稳定型心绞痛患者进行危险分层,对于不稳定型心绞痛的诊断、治疗以及预后具有重要的作用。