腹腔镜下全胃切除术对胃上部肿瘤患者远期生存率的影响

摘要

ObjectiveTo investigate influence by laparoscopic total gastrectomy on long-term survival rate in upper stomach tumor patients.MethodsA total of 100 upper stomach tumor patients were randomly divided into observation group (55 cases) and control group (45 cases). The control group received laparoscopic proximal gastrectomy, and the observation group received laparoscopic total gastrectomy. Postoperative complications and 1, 3, 5 years survival rates of the two groups were observed and recorded.ResultsThere was no statistically significant difference of postoperative incidence of complications as 10.9% and 11.1% between the observation group and the control group (P>0.05). The difference of 1, 3, 5 years survival rates of stages Ⅰ and Ⅱ patients had no statistical significance between the two groups (P>0.05). The difference of 1-year survival rate of stage Ⅲ patients had no statistical significance between the two groups (P>0.05), and their differences of 3 and 5 years survival rates had statistical significance (P<0.05).ConclusionLaparoscopic total gastrectomy shows no precise influence on postoperative incidence of complications and short-term survival rate, while it can improve long-term survival rate in stage Ⅲ patients.%目的：探讨腹腔镜下全胃切除术对胃上部肿瘤患者远期生存率的影响。方法100例胃上部肿瘤患者,随机分为观察组(55例)和对照组(45例)。对照组患者给予腹腔镜下近侧胃切除术,观察组给予腹腔镜下全胃切除术。观察并记录两组患者手术后的并发症发生情况及术后1、3、5年生存率。结果观察组患者术后并发症发生率10.9%与对照组11.1%比较差异无统计学意义(P>0.05)。两组患者中肿瘤分期为Ⅰ、Ⅱ期的患者,其术后1、3、5年生存率比较,差异无统计学意义(P>0.05)；两组Ⅲ期患者术后1年生存率比较,差异无统计学意义(P>0.05),3、5年生存率比较,差异有统计学意义(P<0.05)。结论腹腔镜下全胃切除术对胃上部肿瘤患者术后并发症发生率及近期生存率影响不大,但是可以提高Ⅲ期患者远期生存率。