OBJECTIVE: To investigate the regularity and characteristics of ADR cases in Shanghai jinshan district. METHODS: 3 514 ADR cases were collected from ADR monitoring center in our district during 2009 - 2010, and then analyzed statistically in respect of source, patient's gender, age, drug types, organs or systems involved in ADR, route of administration, etc. RESULTS: The ratio of male to female was 1:1.29; 43.34% ADR were caused by anti-infectious drugs; digestive system injury, lesion of skin and its appendants, nervous system injury were the common symptom, accounting for 29.27% 、26.77% 、11.72% ; most of ADR were caused by intravenous injection, accounting for 61.34%; ADR cases were mainly reported by doctor, accounting for 2 270 cases. CONCLUSION: ADR is common in the clinical treatment. ADR monitoring should be strengthened in-depth to reduce the occurrence of adverse drug reactions as much as possible and achieve safe and effective drug use.%目的:了解上海市金山区药品不良反应(ADR)发生的规律与特点.方法:对我区ADR监测中心2009-2010年收集到的3 514例ADR报告,按申报来源、患者性别、年龄、药品类型、ADR累及器官或系统、给药途径等进行统计、分析.结果:男、女之比为1∶1.29;抗感染药引起的ADR占43.34％；消化系统、皮肤及其附件、神经系统的损害较为常见,分别为29.27％、26.77％、11.72％；注射给药引起的ADR较多,为61.34％；ADR以医师申报为主,有2 270例.结论:ADR在临床药物治疗中较常见,应促进ADR监测工作深入开展,尽可能避免和减少ADR发生,达到安全、有效的用药目的.
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