重庆医院2012年至2014年头孢类抗菌药物用药分析

摘要

Objective To understand the usage information of cephalosporin antibiotics in Chongqing's hospital during 2012-2014. Methods The application of cephalosporins antibiotics in Chongqing was analyzed in respects of consumption sum,defined daily doses(DDDs). Results The total consumption sum of cephalosporins antibiotics in Chongqing from 2012 to 2014 was 142 738. 96 million Yuan,which increased smoothly year by year with an average growth rate of 1. 11%. In these medicines,the most increased medicine was the cefixime,whose average growth rate per annum was 21. 60%,but the cefmenoxime decreased year by year with an average decrease rate per annum of 32. 12%. From 2012 to 2014,DDDs showed some changes in cefuroxime and cefmenoxime. The for-mer was increasing rapidly from 185. 49(∕thousand day)in 2012 to 319. 42(∕thousand day)in 2014 with the average growth rate of 31. 55%. However cefmenoxime decreased obviously year by year with an average decrease rate of 31. 83%,which was correspond to its consumption sum. Other's change was small,some increased and some decreased. Conclusion The varieties,amount and DDDs of the cephalosporin antimicrobial drug application in the hospitals of Chongqing during 2012-2014 increase stably,DDC and B∕A have little changes. At present,the rational clinical use of cephalosporins antibiotics gradually increases,but clinical pharmacist still should strength-en rational clinical use of drugs to ensure patient medication safety.%目的：了解重庆医院2012年至2014年头孢类抗菌药物的应用状况。方法采用用药金额和用药频度（DDDs）对头孢类抗菌药物进行排序并分析。结果2012年至2014年，重庆医院头孢类抗菌药物用药总金额142738.96万元，年均增长1.11％，较平稳，其中头孢克肟增长较快，年均增长21.60％，降幅较大的为头孢甲肟，年均下降32.12％；2012年至2014年，DDDs增长较快的是头孢呋辛，从2012年的185.49（∕千日）升至2014年的319.42（∕千日），年均增长31.55％；头孢甲肟下降较大，与用药金额下降相当，年均下降31.83％，其他药物变化不大，且有增有减。结论重庆医院2012年至2014年应用头孢类抗菌药物的品种金额及DDDs增加均较平稳， DDC及B∕A变化不大。目前头孢类抗菌药物临床应用合理性逐渐加强，但临床药师仍应加强临床合理用药，保证患者用药安全。