Objective To study the clinical efficacy of airway nursing combined with 0. 45% sodium solution and chloride ambroxol in elderly patients with craniocerebral injury after airway open operation. Methods 60 elderly patients with craniocerebral injury after air-way open operation in the hospital treated by 0. 45% sodium solution and chloride ambroxol were divided into the control group ( routine nursing ) and the observation group ( airway nursing ) according to the random number method, 30 patients per group. The arteri-al oxygen pressure, arterial carbon dioxide pressure, and the incidence of pulmonary infection and life quality in two groups were com-pared. Results Compared with the control group, the oxygen partial pressure, carbon dioxide pressure and base excess capacity were sig-nificantly improved after nursing in the observation group ( P < 0. 05 );the incidence of pulmonary infection was obviously reduced in the observation group ( P < 0. 05 ); the each dimenson score and total scores of life quality were significantly increased in the observation group ( P < 0. 05 ) . Conclusion During the treatment of 0. 45% sodium solution and chloride ambroxol in elderly patients with cranio-cerebral injury after airway open operation, the airway nursing can improve the hypoxia symptoms, reduce the respiratory complications, and improve the patients′ life quality after operation.%目的：探讨气道护理联合0．45%氯化钠溶液加盐酸氨溴索用于老年颅脑损伤患者气道切开术后的临床疗效。方法选择医院60例老年颅脑损伤气管切开术患者，均给予0．45%氯化钠溶液加盐酸氨溴索治疗，根据随机数字表法分为对照组（常规护理）和观察组（气道护理），每组各30例。比较两组治疗后氧分压、二氧化碳分压，肺部感染及生活质量。结果与对照组相比，观察组治疗后氧分压、二氧化碳分压均得到明显改善（ P<0．05），肺部感染发生率显著降低（ P<0．05），生活质量各维度得分及总分均明显提高（ P<0．05）。结论老年颅脑损伤患者气道切开术后行0．45%氯化钠溶液加盐酸氨溴索治疗期间，气道护理能够改善缺氧症状，减少呼吸道并发症，提高患者术后生活质量。
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