痤疮合剂的制备及其黄芩苷含量测定

摘要

目的 制备痤疮合剂并测定方中黄芩苷的含量.方法 采用煎煮法制备痤疮合剂,采用三波长紫外分光光度法测定合剂中黄芩苷的含量.结果 黄芩苷质量浓度在3.872～48.530 μg/mL范围内与吸光度值线性关系良好,r=0.994 6(n=7),平均加样回收率为97.40％,RSD=1.76％ (n =5).结论 痤疮合剂的制备方法简便易行,质量可控.%Objective To prepare Acne Mixture and determine the content of baicalin in Acne Mixture.Methods Decoction method was used for production of Acne Mixture and the content of baicalin in the Acne Mixture was determined by three-wavelength ultraviolet spectrophotometry.Results The mass concentration of baicalin had a good linear relationship with the absorbance value in the range of 3.872-48.530 μg/mL(r=0.994 6,n=7),the average recovery was 97.40％,and the RSD was 1.76％ (n=5).Conclusion The preparation method of Acne Mixture is simple,and the quality is controllable.