目的 探讨参芪十一味颗粒在预防131I治疗分化型甲状腺癌所致骨髓抑制的临床效果.方法 选取医院2014年6月至2016年6月收治的行手术治疗后分化型甲状腺癌患者300例,按随机数字表法分为对照组和研究组,各150例.对照组患者术后予131I治疗,研究组在此基础上加用参芪十一味颗粒治疗,观察和比较两组患者的中性粒细胞和白细胞水平.结果 治疗前,两组患者中性粒细胞和白细胞计数比较,差异无统计学意义(P>0.05);治疗4,8周后,研究组患者中性粒细胞和白细胞计数均明显高于对照组(P0.05).结论 参芪十一味颗粒预防131I治疗分化型甲状腺癌所致骨髓抑制疗效明确,预防白细胞及粒细胞减少的效果较佳,安全性高,值得临床推广.%Objective :To observe and analyze the clinical effect of Shenqi Shiyiwei Granules in preventing bone marrow suppression in-duced by 131I in differentiated thyroid cancer. Methods 300 patients with differentiated thyroid cancer who underwent surgical treatment from June 2014 to June 2016 in the hospital were selected and divided into the control group and the study group in accordance with the random number table method, 150 cases in each group. The control group was given 131I treatment, and on this basis, the study group based was given Shenqi Shiyiwei Granules. The neutrophils and white blood cell levels in the two groups were observed and com-pared. Results There was no significant difference in neutrophils and white blood cell count between the two groups before treatment ( P > 0. 05 ) . After 4 and 8 weeks of treatment, the neutrophils and white blood cell count of the study group were significantly higher than those of the control group ( P 0. 05 ) . Conclusion Shenqi Shiyiwei Granules in preventing bone mar-row suppression induced by 131I in differentiated thyroid cancer has clear effect, it is better to prevent white blood cells and granulo-cytes, which is worthy of clinical promotion.
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