首页> 中文期刊> 《中国药业》 >不同镇痛药物对口腔颌面外科术后静脉镇痛的效果与安全性对比分析

不同镇痛药物对口腔颌面外科术后静脉镇痛的效果与安全性对比分析

         

摘要

Objective To investigate the efficacy and safety of sufentanil and lornoxicam on postoperative analgesia effect after oral and maxillofacial surgery. Methods 76 cases of patients who received oral and maxillofacial surgery in the hospital from April 2014 to Au-gust 2016 were selected and randomly divided into two groups. The control group received 1 mg/kg sufentanil+3 mg granisetron+0. 9% sodium chloride 100 mL for postoperative analgesia;the observation group received 32 mg lornoxicam+3 mg granisetron+0. 9%sodium chloride 100 mL for postoperative analgesia. The analgesic scores of 4, 8, 12 and 24 h after surgery in the two groups were recorded and compared, as well as the patients′ satisfaction and the incidence rate of adverse reactions. Results There was no signifi-cant difference in the VAS score and RSS score between the two groupsafter the treatment of different analgesic drugs ( P > 0. 05 ) . The analgesic effect of the control group was 97. 37%, while the observation group was 92. 11%( P > 0. 05 ) . The incidence rate of adverse reaction in the control group was 23. 68%, which was obviously higher than 5. 26% in the observation group ( P 0.05);对照组镇痛效果满意率为97.37%,与观察组的92.11%差异不显著(P>0.05);观察组患者不良反应发生率为5.26%,明显低于对照组的23.68%(P<0.05).结论 口腔颌面外科术后患者应用氯诺昔康自控镇痛,效果与舒芬太尼相似,但不良反应发生率更低,更利于患者康复.

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