中重度慢性阻塞性肺疾病患者6分钟步行试验及其相关因素分析

摘要

Objective: To discuss the relationship of six minute walk test with FEV1%, MMRC and SGRQ in patients with chronic obstructive pulmonary disease. Methods: Six minute walk test (6MWT), pulmonary function, MMRC and SGRQ were detected in 63 patients who were diagnosed moderate to severe COPD. Results: FEV1%, MMRC and SGRQ were cor-related with the 6MWD. MMRC and SGRQ were correlated with 6MWD in step wise multi-variate linear regression analy-sis. Conclusion: 6MWD has close relation with MMRC, FEV1% and SGRQ in the patients with moderate-severe COPD. 6MWT can reflect the clinical condition of COPD.%目的:探讨中重度COPD稳定期患者6 min步行试验(6MWT)与肺功能、呼吸困难及生活质量的相关性.方法:选取中重度COPD患者63例,进行6 min步行试验并测定肺功能、呼吸困难评分(MMRC)、生活质量(SGRQ)等指标.结果:FEV1%、MMRC、SGRQ总评分及活动能力评分、社交心理影响评分与6 min步行距离(6MWD)相关,多元逐步回归分析表明MMRC及活动能力评分与6MWD相关.结论:中重度COPD患者6MWD与MMRC、FEV1%及SGRQ相关.6 min步行试验能反映中重度COPD患者的临床状况.