目的：探讨胃铋镁颗粒预防阿司匹林所致胃黏膜损伤的临床效果。方法将2013年6月~2014年6月在本院老年病科治疗的48例预防阿司匹林所致胃黏膜损伤患者随机分为两组，对照组采用常规疗法，观察组在此基础上加服胃铋镁颗粒，2个月后比较两组的胃黏膜损伤发生率、消化道症状、不良反应等。结果观察组胃黏膜损伤发生率明显低于对照组，差异有统计学意义（P<0.05）；观察组消化道症状积分明显较对照组低，差异有统计学意义（P<0.05）；两组不良反应发生率比较差异无统计学意义（P>0.05）。结论胃铋镁颗粒预防阿司匹林所致胃黏膜损伤的临床效果显著，能有效抑制消化道症状，具有积极的临床意义。%Objective To investigate the clinical efficacy of gastric bismuth magnesium granules in the prevention of aspirin related gastric mucosal injury. Methods 48 patients for prevention on aspirin-induced gastric mucosal injury from June 2013 to June 2014 at geriatric department in our hospital were randomly divided into two groups,the control group was treated with conventional therapy,the observation group was added with gastric bismuth magnesium granules. After treatment for 2 months,the incidence rate of gastric mucosa injury,digestive tract symptom and adverse reaction were compared between two groups. Results The incidence rate of gastric mucosa injury in observation group was sig-nificantly lower than that in control group,with statistical difference(P<0.05).The digestive tract symptoms in observation group was significantly lower than that in control group,with statistical difference (P<0.05).There was no statistical dif-ference of adverse reaction between two groups (P>0.05). Conclusion Clinical efficacy of gastric bismuth magnesium granules in the prevention of aspirin related gastric mucosal injury is remarkable,can effectively inhibit the gastroin-testinal symptom,has a positive clinical significance.
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