Objective To analyze pathological characteristics and risk factors of type 2 diabetic patients with cerebral infarction in senile patients. Methods A total of 219 patients of type 2 diabetes with cerebral infarction data were retro-spective analyze. These patients were divided into three groups. Nine possible risk factors of two groups were compared. Results Comparison of large area,multifocal,and recurrence were statistically significant between the combined group and pure cerebral infarction group(P<0.05). Smoking,hypertension,cholesterol,triglyceride,low density lipoprotein,fibrinogen,hemoglobin were significantly correlated with cerebral infarction(OR=18.367,18.014,4.216,22.341,24.871,6.157,8.149). Conclusion Large area, multifocal, and recurrence infarcts are more common in type 2 diabetes of se-nile patients. Smoking, hypertension, cholesterol, triglyceride, low density lipoprotein, fibrinogen, hemoglobin are risk factors for type 2 diabetes with cerebral infarction in senile patients.%目的：分析老年2型糖尿病合并脑梗死的病变特点和危险因素。方法回顾性分析219例患者的临床资料，分为合并组、单纯脑梗死组及单纯糖尿病组，采用Logistic回归分析法对9项可能的危险因素进行分析。结果老年2型糖尿病合并脑梗死患者大面积脑梗死、多灶性梗死、再发性梗死人数均高于单纯脑梗组(P<0.05)。 Lo-gistic逐步回归分析显示，吸烟、高血压、胆固醇、甘油三酯、低密度脂蛋白、纤维蛋白原、糖化血红蛋白与脑梗死显著相关(OR值分别为18.367、18.014、4.216、22.341、24.871、6.157、8.149)。结论老年2型糖尿病患者合并脑梗死具有大面积性、多灶性和易复发的特点。吸烟、高血压、胆固醇、甘油三酯、低密度脂蛋白、纤维蛋白原、糖化血红蛋白是老年2型糖尿病合并脑梗死的危险因素。
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