血浆同型半胱氨酸升高与脑梗死患者颈动脉硬化的关系分析

摘要

目的：对血浆同型半胱氨酸(Hcy)升高和脑梗死患者颈动脉硬化之间的关系进行研究。方法将2012年9月~2014年9月在我院进行治疗的60例急性脑梗死患者设为研究组，入院次日对其进行空腹抽血、测定Hcy，并进行颈动脉彩超检查，观察是否出现颈动脉硬化。同时，选取同期进行体检的60例健康者作为对照组。结果两组在高血压、糖尿病、低密度脂蛋白及Hcy方面差异有统计学意义(孕<0.05)，在饮酒史、吸烟史、总胆固醇及甘油三酯指标方面比较，无显著性差异(孕>0.05)；多元蕴燥早蚤泽贼蚤糟回归分析发现，血浆匀糟赠水平和颈动脉硬化呈正相关。结论血浆同型半胱氨酸升高也是引起动脉粥样硬化的危险因素之一，且和脑梗死有紧密关系。%Objective To elevated plasma homocysteine (Hcy) the relationship between carotid atherosclerosis and cere-bral infarction patients were studied. Methods 60 patients with acute cerebral infarction from September 2012 to September 2014 in our hospital were collected as the study group. The empty stomach blood, determination of Hcy, and the examination of the carotid artery colour was hospitalized for the next day to exceed, observed whether carotid atherosclerosis. At the same time, 60 cases of healthy subjects of the same period were examined as the control group. Results The two groups had statistical significance in hypertension, diabetes, low-density lipoprotein and Hcy (P<0.05), There was no difference in drinking history, smoking history, total cholesterol and triglyceride index (P>0.05), and mul-tivariate Logistic regression analysis showed that plasma Hcy levels and carotid atherosclerosis were positively correlated. Conclusion Elevated plasma homocysteine is a risk factor for atherosclerosis, and we have close ties and cerebral in-farction.