With diabetes increasing year by year,hypoglycemic drugs are widely recognized and applied,excessive use of hypoglycemic drugs,there may be many side effects.Diabetic patients taking large doses of metformin (glucophage),glimepiride(amaryl),pioglitazone(yiting) after acute renal failure,lactic acidosis,gastrointestinal bleeding,cerebral edema,respiratory failure and a series of complications,according to the characteristics and complications of drug positive blood purification therapy and other select rescue measures,successfully saved the lives of patients,are reported in the following cases.%随着糖尿病患者的逐年增多,降糖药物被广泛的认识和应用,降糖药物的过量应用,可出现诸多副作用。糖尿病患者大剂量服用二甲双胍(格华止)、格列美脲(亚莫利)、吡格列酮(艾汀)后出现急性肾功能衰竭、乳酸酸中毒、消化道出血、脑水肿、呼吸衰竭等一系列并发症,依据药物特性及并发症情况积极选择血液净化治疗及其他抢救措施,成功挽救患者生命,现报道该病例。
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