Pharmaceutical composition comprising Metformin or its Salt acceptable for pharmaceutical use with glimepiride and metformin or its Salt acceptable for pharmaceutical use and glimepiride for the manufacture of a medicament

摘要

A Pharmaceutical composition comprising Metformin or its Salt acceptable for pharmaceutical use, such as hydrochloride, succinate or fumarate with glimepiride Mixed according to different formulations excipients used depend on the ratio of the two active substances.The ratio between the two active substances can be either combinations where Metformin or its Salt acceptable for pharmaceutical use is maintained in the range of 100 to 10000 mg and mg glimepiride is maintained in the range of 0.1 to 20 mg.Use of Metformin or its Salt acceptable for pharmaceutical use and glimepiride for the manufacture of a Medicament useful for Blood glucose control in patients with Type 2 diabetes. Clinical studies have shown a synergistic effect compared with monotherapy. Applies in the field of oral hypoglycemic agents.