西酞普兰治疗脑卒中后抑郁症的临床分析

摘要

目的：探讨西酞普兰治疗脑卒中后抑郁症的临床疗效。方法将60例脑卒中后抑郁症患者随机分为研究组（西酞普兰组）和对照组（多虑平组）。研究组每日晨服西酞普兰20mg；对照组口服多虑平25mg 每日3次。两组连续服用4周。结果治疗4周后，研究组抑郁症的总有效率为93.3%，神经功能缺损的有效率93.4%；对照组抑郁症的有效率56.7%，神经功能缺损的有效率73.3%。两组间差异有统计学意义。结论西酞普兰能有效缓解脑卒中后抑郁症症状，对神经功能缺损的恢复有较大帮助，值得在临床上进一步推广。%Objective To explore the Clinical effect of citalopram in treatment of post-stroke depression. Methods Sixty patients with post-stoke depression were randomly divided into study group(citalopram group) and the control group(doxepin group).Study group every morning 20mg oral citalopram.Control group oral doxepin 25mg three times a day. Both groups were taken for 4 weeks. Results The total effective for treatment of depression the study group is 93.3%,neurologic impairment of the total effective is 93.4%.The total effective for treatment of depression the control group is 56.7%,neurologic impairment of the total effective is 73.3%.A statistically significant difference between the two groups. Conclusion Citalopram can effectively alleviate the symptoms of post-stroke depression,neurologic recovery will be of great help and worth in clinical practice to further promote.