雾化吸入疗法治疗肺结核病的临床疗效观察

摘要

Objective To study the Clinical observation of Inhalation therapy for TB.Methods 136 cases of patients with TB were selected and randomly assigned control group and observation group,with 68 patients in each group.The control group with conventional anti-tuberculosis to treatment,and patients of observation group was used with inhalation of isoniazid,to observe the therapeutic effect and security of two groups. ResultsTwo groups of patients with clinical symptoms was improved significantly,the observation group and improve the situation was better than that of control group(P<0.05);Sputum bacteria turn rate was obviously higher than that of control group (P<0.05),the incidence of adverse reactions to the two groups had no significant difference (P>0.05). Conclusion Inhalation isoniazid has remarkable clinical curative efficacy on MDR-TB,and with less adverse reaction,which is worth of clinical recommendation.%目的：探讨雾化吸入抗结核药物治疗肺结核病的临床效果。方法采用随机数字表法将136例肺结核患者分为观察组和治疗组各68例，对照组采用西医常规抗结核治疗，观察组在对照组治疗的基础上加用异烟肼雾化吸入，观察两组的治疗效果及安全性。结果两组患者临床症状均较治疗前有显著改善，且观察组改善情况优于对照组（P＜0.05）；观察组患者总有效率明显优于对照组（P＜0.05），痰菌转阴率明显高于对照组（P＜0.05）。两组不良反应发生率无统计学意义（P＞0.05）。结论雾化吸入异烟肼治疗肺结核效果较好，不良反应较少，值得临床推广应用。