墨西哥仙人掌多糖对人乳腺癌MCF-7细胞生长抑制作用的研究

摘要

Objective: To observe the inhibitory effect of polysaccharides of mexican cactus on the human breast cancer MCF cells. Methods: The human breast cancer cells cultivated in vitro were treated with polysaccharides of Mexican cactus. The inhibiting effect of polysaccharides of Mexican cactus on the human breast cancer MCF cells was assayed by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) staining method and by inverted microscope. Results: Polysaccharides of Mexican cactus of different concentrations all promote the apoptosis and death of human breast cancer MCF cells. The inhibitory rate on the human breast cancer MCF cells of polysaccharides of Mexican cactus of the highest concentration was 78.7%. Conclusion: Polysaccharides of Mexican cactus can inhibit the growth of human breast cancer MCF cells.%目的:观察墨西哥仙人掌多糖对人乳腺癌MFC-7细胞生长的抑制作用.方法:体外培养人乳腺癌MFC-7细胞,利用四甲基偶氮唑蓝染色法(MTT法)及倒置显微镜观察仙人掌多糖对人乳腺癌MFC-7细胞生长的抑制作用.结果:不同浓度的墨西哥仙人掌多糖均能够促进人乳腺癌MFC-7细凋亡或死亡,最大浓度的墨西哥仙人掌多糖的肿瘤细胞生长抑制率为78.7%.结论:墨西哥仙人掌多糖能够抑制人乳腺癌MFC-7细胞的生长.