目的 探讨影响经鼻内窥镜术后脑脊液鼻漏发生预后因素,为预防脑脊液鼻漏提供参考.方法 选择2005年9月～2011年10月我院收治的180例垂体腺瘤经鼻内窥镜手术的患者,对患者的一般资料、肿瘤特征、手术情况进行统计分析.结果 180例患者治疗后,共发生脑脊液鼻漏25例,发生率为13.9%.单因素Logistic分析显示肿瘤大小、再次手术、慢性蝶窦炎、肿瘤质地、肿瘤边缘与术后脑脊液鼻漏有关,多因素Logistic分析显示肿瘤质地、直径、肿瘤边缘三个因素与术后脑脊液鼻漏有关.结论 肿瘤直径、肿瘤的质地和边缘与经鼻内窥镜手术术后脑脊液鼻漏的发生相关,在实施径鼻内窥镜手术时应更加小心,修补应更仔细.%Objective To Investigate the prognostic factors of cerebrospina] fluid leakage in the endoscopic sinus surgery and to provide a reference for the prevention of cerebrospinal fluid leakage. Methods 180 cases of pituitary adenoma were treated by the endoseopic sinus surgery from February 2005 io October 2011 in our hospital, all patients' general information, tumor characteristics, surgery situation were analyzed. Results 25 cases were found cerebrospinal fluid leakage in the 180 patients, the rate was 13.9%. Tumor size, reoperation, chronic sphenoid sinusitis, tumor texture, tumor margin were related to the postoperative cerebrospinal fluid leakage according to univariate Logistic analysis; the tumor texture, size, tumor margin were related to the postoperative cerebrospinal fluid leakage according to multivariate Logistic analysis. Conclusion The tumor size, texture and margin have the relationship with endoscopic postoperative cerebrospinal fluid leakage, so we should be more careful about the implementation of functional endoscopic sinus surgery and the repair.
展开▼
