Objective To evaluate the quality of life (QOL) after the Ivor Lewis esophageal cancer resection and the left thoracic single-incision esophageal cancer resection.Methods 60 patients with upper or middle section esophageal cancer January 2009 to January 2012 in the People's Hospital of Cangxi County and the Central Hospital of Guangyuan City were selected and divided into Ivor Lewis group and left thoracic group with 30 cases in each group.Patients in Ivor Lewis group were treated with Ivor Lewis esophageal cancer resection and patients in left thoracic group were treated with left thoracic single-incision esophageal cancer resection.QLQ-C30 and QLQ-OES18 made by EORTC were used to evaluate the QOL before the operation and 1,12,24 weeks after the operation.Results Time of operation in left thoracic group [(147±29) min] were shorter than those in Ivor Lewis group [(283±43) min],the difference was statistically significant (P ＜ 0.01); the difference of bleeding volume in the two groups was not statistically significant (P ＞ 0.05).The difference of postoperative complications in the two groups was not statistically significant (P ＞ 0.05).The difference of overall score of QOL before and 1week after the operation in Ivor Lewis group [(81.4±5.3),(83.6±11.2) scores] and left thoracic group [(33.4±13.1),(46.4±11.3) scores] were statistically significant (P＜ 0.05).Pain score 1 week after the operation in Ivor Lewis group and left thoracic group were (78.6±18.5),(57.8±19.1) scores,function scores were (59.4± 16.5),(70.1± 19.7) scores respectively,the difference was statistically significant (P ＜ 0.05); Pain score 24 week after the operation in Ivor Lewis group and left thoracic group were (26.3±28.1),(9.4±15.2) scores,function scores were (88.3±10.4),(95.5±7.4) scores respectively,the difference was statistically significant (P ＜ 0.01).Conclusion The QOL of patients underwent left transthoracic esophagectomy is significantly higher than that in patients underwent Ivor Lewis esophagectomy.%目的 评价Ivor Lewis食管癌切除术和经左胸廓单切口食管癌切除术对患者术后生活质量(QOL)的影响.方法 选取2009年1月～2012年1月苍溪县人民医院和广元市中心医院收治的食管中、上段癌60例,其中行Ivor Lewis食管癌切除术者(Ivor Lewis组)与经左胸廓单切口食管癌切除术者(经左胸廓组)各30例.采用欧洲癌症研究与治疗组织(EORTC)设计的生活质量核心量表(QLQ-C30)和食管癌补充量表(QLQ-OES18),分别于术前及术后1、12、24周采集患者资料.结果 经左胸廓组手术时间[(147±29)min]明显短于Ivor Lewis组[(283±43)min],差异有高度统计学意义(P＜ 0.01)；两组间失血量差异无统计学意义(P＞0.05).Ivor Lewis组术后并发症发生率与左胸廓组比较,差异无统计学意义(P＞0.05).Ivor Lewis组患者术前、术后1周生存质量总体评分[(81.4±5.3)、(83.6±11.2)分]与左胸廓组[(33.4±13.1)、(46.4±11.3)分]比较,差异均有统计学意义(P＜0.05).术后1周Ivor Lewis组与经左胸廓组患者疼痛评分分别为(78.6±18.5)、(57.8±19.1)分,功能评分分别为(59.4±16.5)、(70.1±19.7)分,差异均有统计学意义(P＜0.05)；术后24周Ivor Lewis组与经左胸廓组患者疼痛评分分别为(26.3±28.1)、(9.4±15.2)分,功能评分分别为(88.3±10.4)、(95.5±7.4)分,差异均有高度统计学意义(P＜0.01).结论 与行Ivor Lewis食管癌切除术患者相比,经左胸廓单切口食管癌切除术患者生活质量更高.
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