Objective To explore and analyze the clinical application of integrated care in the combination of advanced pancreatic cancer radiotherapy.Methods From April 2015 to April 2017,90 patients with advanced pancreatic cancer underwent three dimensional conformal radiotherapy synchronous chemotherapy treatment in Xingtai City People's Hospital were selected and divided into control group and observation group by random number table,with 45 cases in each group.The control group was treated by the routine care,the observation group was treated by the comprehensive care,they were treated for two months.The adverse reaction,anxiety,depression and quality of life in the groups were compared.Results The observation group had a lower incidence of nausea and vomiting,diarrhea,constipation,liver and kidney dysfunction,abnormal blood picture,hair loss,and stomatitis compared with the control group,with statisti cally significant difference (P ＜ 0.05).The SAS and SDS scores of the two groups after treatment were decreased than before treatment,the improvement of observation group was more remarkable,with statistically significant difference (P ＜0.05).The physical function,role function,emotional function,cognitive function,social function and overall health in the observation group were higher than those in the control group,with statistically significant difference (P ＜ 0.05).Conclusion The application of integrated care in advanced pancreatic cancer with radiotherapy and chemotherapy can reduce the incidence of toxic side effects,improve the anxiety and depression and improve the quality of life.%目的 探究与分析综合护理干预在晚期胰腺癌放疗联合同步化疗中的临床应用.方法 选取邢台市人民医院2015年4月～2017年4月收治的90例接受放疗同步化疗治疗的晚期胰腺癌患者,采取随机数字表法分为对照组与观察组,每组各45例.对照组给予常规护理,观察组给予综合护理干预,两组均连续护理2个月.对比两组患者毒副作用、焦虑抑郁情绪及生活质量.结果 观察组与对照组相比,恶心呕吐、腹泻便秘、肝肾功能异常、血象异常、脱发及口腔炎发病率较低,差异有统计学意义(P＜0.05).与护理前相比,两组护理后SAS及SDS评分均降低,观察组护理后与对照组护理后相比,SAS及SDS评分改善更加显著,差异有统计学意义(P＜0.05).与对照组相比,观察组躯体功能、角色功能、情绪功能、认知功能、社会功能及总体健康状况评分均较高,差异有统计学意义(P＜0.05).结论 将综合护理干预应用于放疗同步化疗晚期胰腺癌中可降低毒副作用发生率,改善焦虑抑郁情绪,促进提高生活质量.
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