自拟养血祛风汤治疗血虚风燥型慢性湿疹的效果

摘要

Objective To observe the clinical effect of Yangxue Qufeng Decoction of traditional Chinese medicine in the treatment of blood deficiency and wind dryness eczema.Methods Sixty-two patients with chronic eczema in department of dermatology,XIyuan Hospital CACMS from June 2016 to July 2017 were selected and divided into two groups by random number table method,with 31 cases in each group.The treatment group received oral administration of Yangxue Qufeng Decoction,200 mL/time,twice per day.The control group received oral administration of Loratadine 10 mg/d.Patients in two groups were administrated topical medication with Hydrocortisone butyrate,twice per day.The main symptom scores were observed and compared between the two groups,and the efficacy was evaluated.Results There was no statistically significant difference between the two groups before treatment of the main symptom integral (including pruritus degree,psoriasis area,skin lesion shape) (P ＞ 0.05).After treatment,the main symptom integral of the two groups were lower than those before treatment (P ＜ 0.05),and the score of treatment group were lower than those in control group,the differences were statistically significant (P ＜ 0.05).After treatment,the total effective rate in the treatment group was higher than that in control group,the difference was statistically significant (P ＜ 0.05).Conclusion Yangxue Qufeng Decoction has remarkable effect in the treatment of blood deficiency and wind dryness eczema,and can improve the quality of life and the clinical symptoms of patients,which is worthy of clinical promotion.%目的 观察自拟养血祛风汤治疗血虚风燥型慢性湿疹的临床效果.方法 选择2016年6月～2017年7月就诊于中国中医科学院西苑医院皮肤科的62例慢性湿疹患者,按照随机数字表法分为两组,各31例.治疗组口服自拟养血祛风汤200 mL/次,2次/d,对照组口服氯雷他定10 mg/d,两组患者均予丁酸氢化可的松乳膏外用,2次/d.观察并比较两组治疗前后主要症状积分,并评价疗效.结果 两组治疗前主要症状积分(包括瘙痒程度、皮损面积、皮损形态)比较差异无统计学差异意义(P＞0.05);治疗后,两组主要症状积分均较治疗前明显降低(P＜0.05),且治疗组评分低于对照组,差异有统计学意义(P＜0.05).治疗后,治疗组总有效率高于对照组,差异有统计学意义(P＜0.05).结论 自拟养血祛风汤治疗血虚风燥型慢性湿疹疗效显著,能够改善患者的生活质量和临床症状,值得临床推广.