LUNA全身伽马刀输出因子的蒙特卡罗模拟研究

摘要

Objective:Using Monte Carlo simulation method to study the important dosimetric parameter output factor of the LUNA stereotactic body radiotherapy device. Methods:Following the manufacturer’s technical documentation to establish the LUNA stereotactic body radiotherapy device’s Monte Carlo model and after model validation. After referring to the output factor measurement’s detector provided by manufacturer, set the relevant parameters in Monte Carlo model at last, compare and analyze the difference of output factor which provided between by manufacturer and calculated by Monte Carlo simulation. Results:In the range of 3%deviation, under the different collimator of condition, output factors which provided by manufacturers and calculated by Monte Carlo are in good agreement, and the reasons for the difference are also analyzed. Conclusion:LUNA stereotactic body radiotherapy device’s output factors of Monte Carlo simulated research work provides reference and basis for the clinical use and quality control.%目的：利用蒙特卡罗模拟方法，对LUNA全身伽马刀重要剂量学参数输出因子进行研究。方法：采集厂商提供的技术数据文档，建立LUNA全身伽马刀蒙特卡罗模型，模型验证后结合厂商测量输出因子所用探测器，设置蒙特卡罗模型相关参数进行模拟计算，比较分析厂商提供的输出因子与蒙特卡罗模拟计算出输出因子的差异。结果：在3%偏差范围内，不同准直器条件下，厂商提供的输出因子和蒙特卡罗模拟计算得到的输出因子符合性好，并进一步分析了相关差异的原因。结论：LUNA全身伽马刀输出因子的蒙特卡罗模拟研究为该设备的临床使用和质量控制提供了参考和依据。