Three female patients presented with red papules, blister, nodules, scab and depressed scar all over the whole body symmetrically, with systemic symptoms including fever and lymphadenectasis. Biopsy of the skin lesion showed dense infiltration constituting of lymphoid cells in dermis. High titers of IgG antibody to EBV antigen, high copies of EBV-DNA and abnormal lymphocyte immunotype were identified in the sera of the three patients.%3例均为成年女性患者,全身可见对称性分布的红色丘疹、水疱、结节、坏死结痂及凹陷性瘢痕,伴有发热、淋巴结肿大等系统症状。组织病理学示:真皮内淋巴样细胞浸润,部分围绕血管周围浸润。血清中 EB 病毒抗体 IgG 阳性,外周血淋巴细胞有高拷贝的 EB 病毒 DNA。患者外周血免疫分型示异常成熟 T 细胞增生。
展开▼