幼畜肠道miRNAs鉴定及其调控功能的研究进展

摘要

Absorption of immunoglobulins and other nutrients from colostrum is traditionally performed in the small intestine of neonates. It is important to explore the molecular mechanism of intestinal development that contribute to improving nutrients uptake and further for sustaining newborn animals growth,development and health. In this paper,the advance in intestinal tract miRNAs,especially related with intestinal development,immune function,and the relationship between miRNAs and intestinal microbiota were summarized,in order to provide references for miRNAs researches and breeding in neonatal animals.%新生幼畜肠道是吸收初乳中免疫球蛋白等营养物质的主要器官,了解幼畜肠道发育的分子调控机制,对于改善幼畜肠道营养物质吸收和保障肠道生长、发育及健康等具有极其重要的意义.文章综述了幼畜肠道miRNAs的研究进展,特别关注了与幼畜肠道发育、免疫功能以及与肠道微生物间关系方面相关miRNAs的研究现状,以期为今后幼畜肠道miRNAs的研究和早期培育提供参考.