ObjectiveTo analyze the effect of the intervention in the prevention and treatment of the perioperative use of antibiotics in department of general surgery.MethodsIn 2012 our hospital underwent surgery to perioperative antibacterial drugs for the treatment of make a retrospective analysis,and in 2013 of medical personnel in department of general surgery of education and supervision and inspection,to intervention on the prevention and application of antibacterial drugs. Since then,the intervention in 2014,while comparing the results of the analysis of the results obtained from the 2012. Results A total of 180 patients were selected by random sampling method,and 230 patients were selected in 2014. The differences in age, gender,admission time and duration of the patients were not statisticaly significant(P> 0.05). After the intervention,al patients were significantly improved in the aspects of hospitalization expenses,hospitalization days,the percentage of antibiotics and the percentage of hospitalization expenses. The difference of the patients before and after the intervention was statisticaly significant(P< 0.05).ConclusionThe management of perioperative antibiotics can not only protect the rationality of the drug use,but also can effectively prevent the symptoms of infection.%目的：对普外科围术期抗菌药物预防应用的干预效果进行对比分析。方法对我院2012年中行普外科围术期抗菌药物治疗的情况作出回顾性的剖析，并于2013年对普外科医护人员进行宣教以及监督检查，以干预其对抗菌药物的预防应用。此后，于2014年进行干预探究，同时对比分析其与2012年未行干预时剖析所得出的结果。结果利用随机抽取法，于2012年中选取180例患者；于2014年中选取230例患者。所有患者在年龄、性别、入院时间以及病程等方面上所存在的差异性，不具有统计学意义（P>0.05）。行干预之后，所有患者在住院费、住院天数、抗菌药物费及其所占住院费的百分比方面上，均得到了显著的改善。干预前后患者间存在的对比差异性，具有统计学意义（P<0.05）。结论对围术期抗菌药物预防应用行干预管理，不仅能保障用药的合理性，还能起到有效预防患者于术后出现感染症状的作用。
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