Objective Study the clinical features of hepatic bile duct stones combined with bile duct cancer. Methods Retrospectively analyzed clinical data about 30 cases of patients with intrahepatic cholangiocarcinoma accompanying hepatolithiasis from 2005 to 2014 years in our hospital. Results Of the 30 patients with hepatobiliary canceration position in the left lobe of liver in 21 cases,there were 5 cases of right hepatic lobe,left lobe were existed in 4 cases,30 cases of patients with cancerous parts are consistent with the position tube and hepatobiliary calculus,patients with hepatolithiasis diagnosed before as hepatobiliary cancer 12 cases,suspected in 9 cases,postoperative pathological examination were taken diagnosed hepatobiliary cancer,diagnosis rate was relatively low,postoperative patients survived more than 5 years accounted for 60%. Conclusion The probability of progress of hepatolithiasis for hepatobiliary duct carcinoma is very high,but the present stage diagnosis rate is stil relatively low,and the postoperative survival rate is low and prognosis is poor,we need further research on the diagnosis and treatment method.%目的：对肝胆管结石合并肝胆管癌的临床特征进行探讨研究。方法对于2005～2014年这9年间入住我院并确诊为肝胆管结石合并肝胆管癌的30例患者的临床资料和回访记录进行回顾性分析。结果这30例患者肝胆管癌变部位在肝左叶的有21例，肝右叶的有5例，左右叶均存在的有4例，30例患者癌变部位均与肝胆管结石部位一致；肝胆管结石患者术前确诊为肝胆管癌的有12例，疑似的为9例，术后采取病理检查均确诊为肝胆管癌，确诊率比较低下；术后患者存活超过5年的占60%。结论肝胆管结石进展为肝胆管癌的机率很高，但现阶段确诊率还比较低下，且术后存活率较低，预后不良，需要进一步研究确诊及治疗方法。
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