肝胆管结石合并肝胆管癌的临床特征探析

摘要

Objective To study the clinical characteristics of patients with intrahepatic bile duct stones and bile duct carcinoma, to analyze theclinical diagnostic methods and results, and to provide reference for clinical research.Methods From February 2005 to February 2010 in our hospital 40 cases of hepatolithiasis associated with cholangiocarcinoma were randomly divided into observation group and control group, respectively, review the clinical data of patients, analysis of clinical features of patients with treatment.Results 40 cases of hepatic bile duct stones with bile duct cancer patients were treated with different examination, the diagnosis rate was relatively low. Analysis of the actual symptoms of patients with hilar bile duct carcinoma in 12 cases, accounting for 30.0%. Left hepatic bile duct carcinoma in 25 cases, accounting for 62.5%, right hepatic bile duct carcinoma in 3 cases, accounting for 7.5%. Patients underwent surgical treatment, respectively, palliative surgery and resection, 16 cases of patients with radical resection, accounting for 40.0%, palliative surgery was performed in 24 patients, accounting for 60.0% of the patients. 25 patients underwent surgery, the survival time was more than 5 years, accounting for 62.5%.Conclusion Bile duct cancer and liver and gallbladder stone correlation, in the treatment of patients, should adhere to the early diagnosis, early treatment of the principle. Different operation methods for the implementation of the different course of patients with hepatolithiasis associated with cholangiocarcinoma is mainly used in the pathological diagnosis, the diagnosis rate is low, postoperative survival rate is low, for more than ten years duration of patients, should be further detailed examination, early treatment, improve life quality and prolong survival time, improve the treatment effect.%目的：研究肝胆管结石合并肝胆管癌患者的临床特征，分析临床诊断的方法与效果，为临床特征的研究提供参考。方法选取2005年2月~2010年2月，我院收治的40例肝胆管结石合并肝胆管癌患者，随机分为观察组和对照组，分别回顾患者的临床治疗资料，分析患者治疗的临床特征。结果40例肝胆管结石合并肝胆管癌患者分别接受不同的检查，确诊率相对较低。对患者的实际病症进行分析，肝门部胆管癌12例，占30.0％；左肝胆管癌25例，占62.5％；右肝胆管癌3例，占7.5％。患者实施手术治疗，分别为姑息手术和切除手术，16例患者实施根治性切除手术，占40.0％；24例患者实施姑息性手术，占60.0％。25例患者接受手术后，生存时间超过5年，占62.5%。结论胆管癌与肝胆管结石相关，在进行患者的治疗时，应该坚持早诊断、早治疗的原则。对不同病程的患者实施不同的手术方法，肝胆管结石合并肝胆管癌主要是应用病理诊断，诊断率较低，手术后的存活率较低，对于病程超过十年的患者，应该进一步进行详细检查，尽早接受治疗，提高生活质量，延长生存时间，提高治疗的效果。