50例老年患者口服胺碘酮所致不良反应临床分析

摘要

目的：分析老年患者口服胺碘酮高龄所致的不良反应及其临床特征。方法对2013年1月～2014年1月本院收治的50例老年患者实施胺碘酮口服治疗，随访24个月，分析不良反应发生情况。结果本组患者不良反应发生率为40.0%（20/50），包括甲状腺功能减退、肺纤维化、窦房阻滞及甲状腺功能亢进等。结论高龄患者口服胺碘酮极易出现各种不良反应，需严格掌握药物使用剂量，及时观察患者生命体征变化情况，减少不良反应的发生，提升患者生活质量。%Objective To analyze the adverse effects and clinical characteristics of elderly patients with oral amiodarone. Methods 50 cases of elderly patients with oral amiodarone therapy on January 2013 to January 2014 in our hospital,after 24 months of fol ow-up,the incidence of adverse reaction was analyzed. Results The incidence of adverse reactions in this group of patients rate was 40.0%(20/50),including thyroid dysfunction,pulmonary fibrosis,sino atrial block and thyroid function hyperfunction. Conclusion Elderly patients with oral amiodarone prone to various adverse reactions,need to strictly control the dosage,to observe the change of vital signs of patients,reduce the incidence of adverse reactions,improve the quality of life of patients.