分析血清细胞因子和红细胞免疫指标与轮状病毒腹泻的关系

摘要

目的：探讨血清细胞因子和红细胞免疫指标与轮状病毒腹泻的相关性。方法入选患者均采用郭氏法检测血清细胞因子与红细胞指标。结果试验组TNF-α、IL-10以及hs-CRP指标高于对照组（P＜0.05），试验组IL-2低于对照组（P＜0.05）。结论轮状病毒腹泻患者血清细胞因子和红细胞指标关系密切，临床应动态监测患者血清细胞因子和红细胞指标，提高临床诊断、治愈率。%Objective To investigate the correlation of serum levels of cytokines and RBC immune index with rotavirus diarrhea. MethodsThe serum cytokines and red blood cell markers of patients wih rotavirus diarrhea were detected by the Guo's method.Results The TNF-α, IL-10 and hs-CRP levels in the experimental group were signiifcantly higher than those in the control group (P< 0.05). The IL-2 level in the experimental group was lower than that in the control group (P< 0.05).Conclusion The relationship between serum cytokines and erythrocyte parameters in patients with rotavirus diarrhea is closed, and the clinical parameters of serum cytokines and red blood cells should be monitored dynamically to improve the clinical diagnosis and cure rate.