奥拉西坦与茴拉西坦治疗血管性痴呆疗效对比性研究

摘要

Objective To contrast research olathe tanks and Hui raschig jotham the clinical curative effect of the treatment of vascular dementia. Methods Choose 96 cases of vascular dementia patients,randomly divided into two groups,the treatment group(olathe jotham group)48 cases,give olathe jotham 0.4 g,3 times/day,Control group(Hui raschig jotham group)48 cases,give Hui raschig jotham 0.2 g,3 times/day,two groups of treatment are for 90 days. All patients were in before treatment and after treatment were applied MMSE and ADL,NIHSS evaluation its curative effect. The two groups of patients before and after treatment,MMSE ADL,NIHSS score changes were analyzed by t test. Results The tanzi olathe patients MMSE and ADL,NIHSS score change is significantly better than that in control group(P < 0.05). Conclusion Olathe tanks can improve the cognitive function of patients with vascular dementia, and the curative effect is better than the Hui raschig jotham, no bad reaction.%　　目的对比研究奥拉西坦与茴拉西坦治疗血管性痴呆的临床疗效.方法选择96例血管性痴呆患者,随机分成两组,治疗组(奥拉西坦组)48例,给予奥拉西坦0.4 g,3次/日；对照组(茴拉西坦组)48例,给予茴拉西坦0.2 g,3次/日,两组疗程均为90 d.所有患者均在治疗前和治疗后分别应用MMSE、ADL、NIHSS测评其疗效.对两组患者治疗前后MMSE、ADL、NIHSS评分变化采用t 检验进行分析.结果奥拉西坦组患者MMSE、ADL、NIHSS评分改变显著优于对照组(P <0.05).结论奥拉西坦能改善血管性痴呆患者的认知功能,且疗效优于茴拉西坦,无不良反应.