小剂量地西泮联合莫沙比利治疗功能性消化不良效果分析

摘要

Objective To investigate the application value evaluation for functional dyspepsia patients by small doses of diazepam combined with mosapride. Methods One hundred and seventy-two functional dyspepsia patients who were treated in the depart-ment of gastroenterology of the hospital of traditional Chinese medicine in jiashan county of jiaxing city in zhejiang province hospi-tal from April 2010 to April 2012 were divided into the control group and the observation group by random number table. The control group were only given mosapride,the observation group were given small doses of diazepam combined with mosapride. Then clinical efficacy and adverse reactions rate were compared. Results The total efficiency rate of the observation group were statisti-cally higher than that of the control group (95.35%vs86.05%,P<0.05),there was no statistically different between the observation group and the control group (9.30%vs16.28%,P>0.05). Conclusion The clinical efficacy of functional dyspepsia patients by small doses of diazepam combined with mosapride is sure,it is superior to mosapride alone,it has the characteristics of safe and reliable and less adverse reactions.%目的：探究功能性消化不良患者运用小剂量地西泮联合莫沙必利治疗的临床效果。方法应用随机数字表法将该院消化科2012年6月—2014年6月间治疗的172例功能性消化不良患者分为对照组和观察组，对照组给予口服莫沙必利进行治疗，观察组在此基础上给予小剂量地西泮进行治疗，比较两组患者的临床治疗效果和不良反应的发应率。结果观察组的临床治疗效果明显优于对照组，差异有统计学意义(95.35%vs86.05%,P<0.05)。观察组患者与对照组比较，药物不良反应发生情况差异无统计学意义(9.30%vs16.28%,P>0.05)。结论对于消化性功能不良患者运用小剂量地西泮联合莫沙必利进行治疗的临床效果较为显著，优于单用莫沙必利治疗者，具有安全高效和不良反应少等特点。