Objective To detect the blood flow velocity and blood flow of fetal umbilical vein and venous catheter in the second and third trimester of pregnancy so as to determine the level of growth and development of the fetus supplemented by color Doppler ultrasound. Methods Color Doppler ultrasound was used to detect the general fetal development and the lumen diameter, blood flow velocity and blood flow of fetal umbilical vein and venous catheters of its terminal branches in the 60 normal healthy pregnant women with the gestational age of 17 to 40 weeks undergoing the prenatal examination from October 2013 to October 2014. Results There were significant differences in the mean values of blood flow parameters of fetal umbilical vein and the ve-nous catheter between the second and the third trimester of pregnancy, by t test, P<0.001. The difference in the mean ratio of fetal venous catheter blood flow to fetal umbilical vein blood flow, and that in the mean ratio of intrahepatic umbilical vein perfusion to fetal umbilical vein blood flow between the second and the third trimester of pregnancy were not significant, by t test, P>0.05. Conclusion The blood flow velocity and perfusion of fetal umbilical vein and venous catheters in the second and third trimester of pregnancy increase with the increase of gestational age. The intrahepatic umbilical vein perfusion also rises with the increase of gestational age, which increases by 57.97%, 60.68%, in the second trimester and third trimester of pregnancy, respectively, playing preferential interaction in maintaining the development and growth of the fetus.%目的：该研究检测孕中晚期胎儿脐静脉及静脉导管的血流速度和血流量，以彩色多普勒超声辅助判定胎儿的发育生长的水平。方法对2013年10月—2014年10月产前检查的正常妊娠17~40周的健康孕妇60例，应用彩色多普勒超声检探测胎儿一般发育状况的同时检测胎儿脐静脉及其末支静脉导管的管腔内径、血流速度及血流量。结果妊娠中期与妊娠晚期胎儿的脐静脉和静脉导管的各项血流参数的均值进行t检验，差异有统计学意义（P＜0.001）。妊娠中、晚期胎儿静脉导管血流量与脐静脉血流量比及脐静脉肝内灌注量与脐静脉血流量比均值进行t检验，差异无统计学意义（P＞0.05）。结论妊娠中晚期胎儿脐静脉及静脉导管血流速度、灌注量随着孕龄的增大而增加。对应脐静脉肝内灌注血流量也随孕龄增大而增加，妊娠中晚期分别为57.97%及60.68%，对维持胎儿的发育生长起优先作用。
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