目的：探讨阿托伐他汀钙在急性脑梗死(CI)并高脂血症(HPL)与颈动脉粥样硬化斑块(CAS)病人中的应用效果。方法整群选择2013年6月—2015年6月该院收治的急性CI并HPL与CAS患者84例,将其平均分为研究组与对照组。对照组给予降血糖、降血压、抗血小板等药物治疗,研究组在此基础上应用阿托伐他汀钙片治疗。结果研究组治疗后颈动脉IMT(1.0±0.5)mm与血脂TG(1.5±0.4)mmol/L、TC(4.1±0.7)mmol/L、LDL(1.7±0.3)mmol/L水平显著低于对照组的(1.6±0.3)mm、(1.8±0.5)mmol/L、(5.8±0.7)mmol/L、(3.4±0.6)mmol/L(P<0.05),HDL(2.1±0.5)mmol/L高于对照组(1.7±0.5)mmol/L(P<0.05)。两组未见明显的药物不良反应。结论阿托伐他汀钙在急性CI并HPL与CAS病人中的应用效果显著,适于推广。%Objective To discuss the application effect of atorvastatin calcium in patients with acute cerebral infarction, hyperlipemia and carotid atherosclerotic plaque. Methods 84 cases of patients with atorvastatin calcium in patients with acute cerebral infarction, hyperlipemia and carotid atherosclerotic plaque admitted and treated in our hospital from June 2013 to June 2015 were selected and randomly divided into two groups, the control group were treated with the drugs including antidiabetics, hypotensive and antiplatelet, the research group were treated with atorvastatin calcium on this basis. Results The carotid artery IMT and blood fat TG, TC and LDL levels in the research group were obviously lower than those in the control group, [(1.0 ±0.5) mm, (1.5 ±0.4) mmol/L, (4.1 ±0.7) mmol/L, (1.7 ±0.3) mmol/L vs (1.6 ±0.3) mm, (1.8 ±0.5) mmol/L, (5.8±0.7) mmol/L, (3.4±0.6 ) mmol/L] (P<0.05), and the HDL in the observation group was higher than that in the control group, [(2.1±0.5) mmol/L vs (1.7±0.5) mmol/L] (P<0.05), and the two groups were without obvious adverse reactions of drugs. Conclusion The application effect of atorvastatin calcium in patients with acute cerebral infarction, hyperlipemia and carotid atherosclerotic plaque is obvious, which is suitable for promotion.
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