血浆脑钠肽水平与慢性心力衰竭严重程度及预后关系

摘要

目的 分析慢性心力衰竭的严重程度与血浆脑钠肽水平的关系和预后效果.方法 选取2014年3月—2017年12月我院收治的慢性心力衰竭患者81例作为研究对象.根据纽约心脏病协会(NYHA)心功能分级标准为其进行分组,分别对应为A组、B组、C组,每组各27例.分析三组患者的血浆脑钠肽水平、左心室射血分数以及左心室舒张末期内径等.结果 相比于C组,A组和B组患者的血浆脑钠肽水平以及左心室舒张末期内径较低,左心室射血分数较高;B组和C组患者中血浆脑钠肽水平升高程度相比于A组较高,血浆脑钠肽水平升高的患者的相比于血浆脑钠肽水平正常患者的死亡率、住院次数较高,住院时间明显较短,组间对比,差异具有统计学意义(P＜0.05).结论 对于慢性心力衰竭患者而言,其血浆脑钠肽水平可充分反应心功能情况,对病情严重度和预后效果具有一定判定价值.%Objective To analyze the relationship between the severity of chronic heart failure (CHF) and plasma brain natriuretic peptide (BNP) levels and its prognostic effect. Methods From March 2014 to December 2017, 81 patients with chronic heart failure were enrolled in this study. They were divided into group A, group B and group C according to the New York Heart Association (NYHA) , 27 cases in each group. The levels of plasma brain natriuretic peptide, left ventricular ejection fraction and left ventricular end-diastolic diameter were analyzed. Results Compared with group C, group A and group B had lower plasma brain natriuretic peptide levels and left ventricular end-diastolic diameter, higher left ventricular ejection fraction, higher plasma brain natriuretic peptide levels in group B and group C than in group A, and higher plasma brain natriuretic peptide levels in patients with normal plasma brain natriuretic peptide levels. The mortality and hospitalization times were higher, the hospitalization time was shorter, and the difference between groups was significant (P < 0.05). Conclusion For patients with chronic heart failure, the level of plasma brain natriuretic peptide can fully reflect the condition of cardiac function, and has certain value in judging the severity of the disease and prognosis.