沙美特罗替卡松联合百令片治疗稳定期老年慢性阻塞性肺疾病合并左心衰竭的疗效

摘要

Objective To analysis stable chronic obstructive pulmonary disease combined with left heart failure patients receiving salmeterol and lfuticasone propionate clinical results combine with bailing pian treatment. Methods Selected 154 cases of heart failure patients with geriatric stable chronic obstructive pulmonary disease as object, were divided into three groups, A group had 53 cases used of salmeterol and lfuticasone propionate in the treatment of joint bailing, Group B had 51 cases embodiment used salmeterol and fluticasone propionate therapy, group C had 50 cases embodiment used bailing tablets in the treatment, compared to the three treatment groups.Results Before treatment, compared group FEV 1, FVC, FEV 1 / FVC, PaO2, PaCO2 and BODE index score,P>0.05, had no difference statistically significance. After treatment, A group FEV 1, FVC, FEV 1 / FVC, PaO2 were higher than before treatment and group B, C, PaCO2 and BODE index score was lower than before treatment and B, and group C,P<0.05, had difference statistically signiifcance. A group LHF AECOPD or acute episodes was higher than group B, C,P<0.05, had difference statistically significance. Compared the incidence of adverse reactions of the three groups,P>0.05, had no difference statistically significance.Conclusion The stability of elderly patients with chronic obstructive pulmonary disease with left heart failure patients receiving treatment with salmeterol lfuticasone propionate and bailing sheet for use in combination with very good results, safe and reliable, lung function and blood gas analysis in patients with test results improved quality of life gained promotion.%目的：分析稳定期老年慢性阻塞性肺病合并左心衰患者接受沙美特罗替卡松联合百令片治疗的临床效果。方法选取我院内科老年稳定期慢性阻塞性肺疾病合并左心衰患者154例来进行研究分析，将这些患者分成3组，A组53例使用沙美特罗替卡松联合百令片治疗；B组51例使用沙美特罗替卡松治疗；C组50例使用百令片治疗，对比3组的治疗效果。结果治疗前，组间FEV 1、FVC、FEV 1/FVC、PaO2、PaCO2和BODE指数评分比较，P＞0.05，差异不具有统计学意义。治疗后，A组FEV 1、FVC、FEV 1/FVC、PaO2均高于治疗前和B、C组，PaCO2和BODE指数评分低于治疗前和B、C组，P＜0.05，差异具有统计学意义。A组AECOPD或急性LHF发作次数高于B、C组， P＜0.05，差异具有统计学意义。3组的不良反应发生率对比，P＞0.05，差异不具有统计学意义。结论稳定期老年慢性阻塞性肺疾病合并左心衰患者接受沙美特罗替卡松和百令片联合使用的治疗方式，具有非常好的效果，安全可靠，患者的肺功能和血气分析检验结果有所改善，生活质量获得了提升。