免疫预防乙型肝炎病毒母婴传播的效果观察

摘要

目的：分析免疫预防阻断乙肝病毒母婴传播的效果。方法对我院2008～2014年乙肝病毒携带孕妇及其8～12月龄婴儿342对，检测乙肝血清标志物及HBV-DNA。完成调查表。对所得数据采用多因素Logistic回归分析。结果单纯使用乙肝疫苗进行免疫组的婴儿感染率高于联合免疫组，有统计学意义（P＜0.05）。结论乙肝病毒携带孕妇的婴儿应采用主被动联合免疫。%Objective To analyze the effect of blocking the immune prevention of perinatal transmission of hepatitis B virus.Methods The hospital in 2008~2014 hepatitis B virus carrier pregnant women and their infants 8~12 months of age 342 pairs to detect HBV serum markers and HBV-DNA. Complete the survey. The resulting data using multivariate Logistic regression analysis.Results The simple use of hepatitis B vaccine in infant infection than immunohistochemistry combined immunodeifciency group was statistically significant (P<0.05).Conclusion The hepatitis B virus carrier mothers of infants should be used in pregnant women passive combined immunodeifciency.