阿托伐他汀钙联合阿司匹林预防性治疗脑梗死后再发的临床疗效观察

摘要

Objective To evaluate the joint aspirin atorvastatin calcium preventive treatment the clinical curative effect of cerebral infarction after again hair.Methods 300 cases of patients with cerebral infarction were chosen in our hospital, were randomly divided into observation group and control group. Observation group were treated by joint aspirin atorvastatin calcium treatment, the control group with simvastatin combined aspirin therapy. After treatment, two groups of patients were observed 6 months after treatment and 1 years after the follow-up of the indicators.Results The two groups of patients after 6 months of treatment, TG, TC, HDL and LDL comparison, the differences were statistically signiifcant (P<0.05). In the observation group, 13 cases of cerebral infarction were followed up for 1 years, accounting for 8.67%. There were 29 cases of recurrent cerebral infarction in the control group, accounting for 19.33%, the difference was statistically significant (P<0.05).Conclusion Atorvastatin calcium combined with aspirin in the prevention of cerebral infarction patients, to prevent the occurrence of secondary cerebral infarction effect is signiifcant.%目的：探讨阿托伐他汀钙联合阿司匹林预防性治疗脑梗死后再发的临床疗效。方法将我院收治的脑梗死患者300例，随机分为观察组和对照组。观察组患者采用阿托伐他汀钙联合阿司匹林治疗，对照组采用辛伐他汀联合阿司匹林治疗。治疗后观察两组患者治疗6个月后及随访1年后各项指标情况。结果两组患者治疗6个月后的TG、TC、HDL和LDL的比较，各个指标差异有统计学意义（P＜0.05）。观察组随访1年中再发脑梗死的人数13例，占8.67%。对照组中再发脑梗死的人数29例，占19.33%，比较差异均有统计学意义（P＜0.05）。结论阿托伐他汀钙联合阿司匹林可预防性治疗脑梗死患者，对预防再次脑梗死的发生效果显著。