对比分析液基细胞学检查与宫颈活检组织病理学诊断

摘要

目的：探讨宫颈活检组织病理学诊断和液基细胞学检查的符合率，探讨其对宫颈病变患者的临床应用效果。方法根据2008年1月～2009年7月我院接收的1548例门诊宫颈患者来分析，其接受了液基细胞学检查，存在异常情况，使用阴道镜下多点活检来进行诊断分析。结果 TCT显示：ASC+AGC 776例（50.1%）；ASC-H 112例（7.2%）；LSL 474例（30.6%）；HSL 186例（12.0%）。宫颈活检为慢性宫颈炎578（37.3%），CINⅠ602例（38.8%），CIN Ⅱ200例（12.9%）， CIN Ⅲ（含原位癌）154例（9.9%，重度不典型增生140例，原位癌14例），宫颈浸润癌14例（0.9%）。结论宫颈病变在液基细胞学和组织病理学诊断中的结果比较一致，两者联合使用可以降低误诊漏诊几率，尽早确诊采取治疗措施，避免延误病情。%Objective To investigate the diagnosis and the coincidence rate of liquid based cytology of cervical biopsy and investigate and to study the clinical effect on patients with cervical lesions.Methods 1 548 cases of cervical outpatients from January 2008 to July 2009 in our hospital were analyzed, they were accepted liquid based cytology, there were abnormal situation, and used colposcopic multiple biopsy for diagnosis.Results TCT showed that ASC+AGC was 776 cases (50.1%); ASC-H112 cases (7.2%); 474 cases of LSL (30.6%); HSL was 186 cases (12.0%). Cervical biopsy for chronic cervicitis was 578 cases(37.3%), CINⅠwas 602 cases (38.8%), CINⅡwas 200 cases (12.9%), CINⅢ (including carcinoma in situ) was 154 cases (9.9%, 140 cases of severe dysplasia, 14 cases of carcinoma in situ), 14 cases of invasive cervical cancer (0.9%).Conclusion The results of cervical lesions in pathological diagnosis of liquid based cytology and tissue is relatively consistent, the combination can reduce the misdiagnosis rate of early diagnosis and treatment measures, to avoid the delay of illness.