评价补硒治疗自身免疫性甲状腺炎（AITD）的效果和安全性

摘要

Objective To investigate the treatment of autoimmune thyroiditis of selenium (AITD) effect and safety. Methods A total of 100 cases of patients with autoimmune thyroiditis were randomly assigned to treatment group method. The control group of 50 patients received conventional treatment, the observation group of 50 cases on this basis also for the treatment of selenium supplement, analysis and comparison of clinical efifcacy.Results Known in the comparison between groups, observation group in anti thyroglobulin antibody and anti thyroid peroxidase antibody were signiifcantly decreased, while the control group showed a rising trend, group compared with statistical signiifcance (P<0.05). There were no obvious adverse reactions in the two groups.Conclusion Selenium treatment of autoimmune thyroiditis (AITD) has better clinical effect and high safety.%目的：探讨补硒治疗自身免疫甲状腺炎（AITD）的效果和安全性。方法我院收治自身免疫性甲状腺炎患者共100例，以随机分配法对患者进行分组处理。对照组50例接受常规治疗；观察组50例在此基础上进行补硒治疗，分析比较临床疗效。结果组间比较可知，观察组患者在抗甲状腺球蛋白抗体及抗甲状腺过氧化物酶抗体测定上显著下降，而对照组患者则呈升高趋势，组间比较差异具有统计学意义（P＜0.05）。两组患者均未出现明显不良反应。结论补硒治疗自身免疫性甲状腺炎（AITD）具有较好的临床效果及较高的安全性。