厄贝沙坦联合索他洛尔对阵发性心房纤颤治疗的临床疗效分析

摘要

Objective To study the clinical efifcacy of irbesartan combined with sotalol in treatment of paroxysmal atrial fibrillation.Methods 100 cases of patients with paroxysmal atrial fibrillation were selected in our hospital and randomly divided into S group with sotalol therapy, group S+E with irbesartan combined with sotalol in the treatment. The treatment effect was compared.Results Sinus rhythm maintenance of two groups was similar in 3 months and half a year (P>0.05), sinus rhythm maintenance ratein 1 year of S+E group was higher(P<0.05), Left atrial diameters of two groups before treatment are similar (P>0.05), Left atrial diameter of S+E group expanded more slowly after treatment for 3 months,6 months,1 year compared to S group (P<0.05).Conclusion Irbesartan combined with sotalol has more deifnite clinical effect in the treatment of paraxysmolatrial ifbrillation, prevent atrial ifbrillation and delay the left atrial enlargement better.%目的：研究厄贝沙坦联合索他洛尔对阵发性心房纤颤治疗的临床疗效。方法选取我院100例阵发性心房纤颤患者。随机分组，S组采用索他洛尔治疗；S+E组采用厄贝沙坦联合索他洛尔治疗。对比两组治疗效果。结果两组3个月、半年窦性心律维持率相似，P＞0.05；S+E组1年窦性心律维持率更高，P＜0.05；治疗前两组左心房内径相似，P＞0.05；治疗3个月、半年、1年S+E组比S组左心房内径扩大更慢，P＜0.05。结论厄贝沙坦联合索他洛尔对阵发性心房纤颤治疗的临床疗效确切，可更好预防心房颤动，延缓左心房扩大。