石蒜属植物中加兰他敏的研究进展

摘要

As the major biological activity component in the bulb of Lycoris Herb., galanthamine has attracted tremendous attentions due to its obvious therapeutic effects in infantile paralysis and Alzheimer. Current research progress on chemical structure, extraction and purification, chemical synthesis and molecular structure modification, structure identification and analysis method of galanthamine are summarized. Meanwhile, the future research outlook of galanthamine is proposed.%加兰他敏是石蒜鳞茎中主要活性成分之一,近年来因其在治疗小儿麻痹后遗症、老年痴呆等方面效果显著成为研究热点.该文对国内外石蒜属植物中加兰他敏的结构、提取与分离方法、化学合成与分子结构改造、结构鉴定与分析方法等方面的研究进行了综述,并在此基础上提出其今后研究发展方向.