The objectives of this study were to explore the effect of different dietary NFC/NDF ratios on ruminal and blood endotoxin and histamine concentrations^ Guanzhong dairy goats with permanent ruminal cannulae were divided into 4 groups and each time lasted for 10 d according to self-contrast design experiment. The goats were fed diets with different NFC/NDF ratios, which the ratios were 1. 02( I group) ,1. 24( II group) , 1. 63( ]TJ group) and 2. 58 (IV group) .respectively. The results showed that with dietary NFC/NDF ratios increased,ruminal endotoxin and histamine increased. Resulting in blood endotoxin and histamine increasing. When NFC/NDF ratio was 2. 58, concentrations of histamine and endoxin in blood and rumen increased significantly with the development of SARA,indicating that increased release of histamine and endotoxin in blood and rumen played an important role in the development of SARA.%试验旨在研究日粮不同非纤维性碳水化合物/中性洗涤纤维(NFC/NDF)对瘤胃液和血液中内毒素和组织胺含量的影响.选择3只安装有永久性瘤胃瘘管的关中奶山羊作为试验动物,采用自身对照试验法,依次饲喂NFC/NDF分别为1.02(Ⅰ组)、1.24(Ⅱ组)、1.63(Ⅲ组)、2.58(Ⅳ组)的4种日粮.结果表明,随着日粮NFC/NDF的提高,瘤胃液中内毒素和组织胺含量随之提高,导致血浆中内毒素和组织胺含量相应增加.当日粮NFC/NDF为2.58时,SARA发生,瘤胃液和血液中内毒素含量随病程发展显著升高(P<0.05),瘤胃液中组织胺含量也随病程发展显著升高(P<0.05).因此,内毒素、组织胺对促进SARA发生、发展起着重要的作用.
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