Swine vesicular stomatitis is a highly contagious viral disease caused by vesicular stomatitis virus. Clinical characteristics of pigs lips, the nose, mouth, blisters and drooling from the mouth repeatedly assured, sometimes often also occur in the skin of the hoof crown and toes, their symptoms to blisters. VSV has widely spread in many parts of the world. In recent years, because the increase of he product trade swine vesicular stom-atitis virus also spreads into our country. Because Swine vesicular stomatitis has similar clinical symptoms with swine vesicular disease, swine foot and mouth disease and swine vesicular rash, so it is particularly important to make the accurate diagnosis and prevention. In VSV vaccine research, mainly are inactivated vaccine and attenu-ated vaccine, and little research of new vaccines. This paper reviews the research progress of swine vesicular stom-atitis virus gene and its vaccine, so as to provide reference for further understand and prevention of this disease.% 猪水疱性口炎是由水疱性口炎病毒引起的高度接触传染性的病毒性疾病。其临床特征为猪的唇部，鼻及口腔等处发生水疱，并从口中不断向外流涎，有时常常还发生在蹄冠和趾间皮肤上，其症状主要以水疱为主。该病在全球许多地区造成广泛流行。近年来，由于产品贸易量的增加，猪水疱性口炎病毒也陆续的传入我国。由于该病与猪水疱病、猪口蹄疫和猪水疱性疹等病毒性疾病容易混淆，因此对该病做出准确地诊断与防制显得尤为重要。在 VSV 疫苗的研究方面，主要是灭活疫苗和弱毒疫苗的研究，而在新型疫苗的研究方面很少。本文主要综述了猪水疱性口炎病毒的基因及其疫苗的研究进展，为进一步了解和预防该病提供参考依据
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