2014年长沙市中心城区犬只狂犬病免疫效果评估

摘要

为了解长沙市中心城区犬只狂犬病免疫抗体水平，给相关职能部门提供科学的防控依据，通过不定期采集全市城区17家授权免疫点犬只血样，使用法国SYBIOTICS犬猫狂犬病抗体检测试剂盒进行抗体水平检测。结果显示：2014年长沙市中心城区犬只狂犬病免疫抗体合格率为65.4%；6月龄以下犬只免疫抗体水平较低，仅为25.6%；免疫一次与免疫两次以上的抗体合格率差异性显著（P<0.05）；免疫两次不同生产厂家疫苗的抗体合格率差异性显著（P<0.05）；免疫三次及以上不同生产厂家疫苗的免疫抗体合格率差异不显著；国产疫苗比进口疫苗的免疫抗体水平要高，但差异不显著。结果提示，应重点关注6月龄以下犬的免疫工作；免疫程序需进一步优化；应继续加大对国产疫苗免疫效果的评估。%In order to know the dog rabies antibody level of the downtown area of Changsha City and provide technical supporting for the relevant functional departments for prevention and control,the blood samples of vaccinated dogs were collected in 17 authorized immune points all over the city,and the antibody-level detection were conducted with the French SYBIOTICS dogs and cats rabies antibody detection kits. The results showed:The overall rate of rabies immune antibody with protective level was 65.4% in downtown area of Changsha City in 2014;for dogs under 6-month-old was 25.6%,relevantly lower. The results also showed: the difference of the rate of antibody with protective level was signifi-cant(P<0.05) between one time vaccination and two times;and the difference was significant (P<0.05)between two time vaccination by using two different vaccines produced by different manufacturers;The difference was not significant be-tween three or more time vaccination by using two different vaccines produced by different manufacturers;The immune antibody level of domestic vaccine was higher than that of the imported vaccine,but the difference was not much signifi-cant. The result suggested the vaccination of dogs under 6 months should be focused on,the immune schedule should be further optimized,and the evaluation of the immune effect of domestic vaccines should continue to be strengthened.