双齿有机膦二茂铁钯(Ⅱ)配合物的合成和催化活性

摘要

Four palladium(Ⅱ) complexes of organic bidentate phosphine ferrocene,[(dppf) PdCl2],[(dtbpf)PdCl2],[(dppf) PdBr2],[(dtbpf) PdBr2],were prepared via a direct reaction in an inert atmosphere using Na2PdX4 (X =C1,Br) as the palladium precursor and the corresponding phosphine ferrocene as the ligand (dppf =1,1'-bis(dipheny-phosphino) ferrocene,dtbpf =1,1'-his (di-tert-butylphosphino) ferrocene).The complexes were characterized by 1 H NMR.The catalytic performance of the complexes was evaluated not only in three well-kunown coupling reactions (Suzuki,Sonogashira and Heck coupling reaction) but also in the coupling reaction between 2-hydroxypyridine and boronic acid reagent.The results showed that the complexes are stable and can efficiently catalyze a series of coupling reactions in a non-protective atmosphere.The catalyst not only has high catalytic activity in unilateral Sonogashira coupling reaction,but also has good selectivity,showing a good application prospect.%以1,1'-双(二苯基膦)二茂铁(dppf)、1,1'-双(二叔丁基膦)二茂铁(dtbpf)为配体,合成了一类双齿有机膦二茂铁钯(Ⅱ)配合物[(dppf) PdCl2]、[(dtbpf) PdC12]、[(dppf) PdBr2]和[(dtbpf) PdBr2],通过核磁共振对配合物进行化学结构表征.评价了它们对Suzuki偶联反应、Sonogashira偶联反应、Heck偶联反应以及2-羟基吡啶与硼酸试剂之间的偶联反应的催化作用.结果表明,配合物化学性质稳定,在非保护气氛下能高效地催化一系列偶联反应.催化剂在单边Sonogashira偶联反应中不但具有较高的催化活性,而且有很好的选择性,显示出很好的应用前景.