取代芳甲酰哌嗪新衍生物的合成及其药理活性

摘要

We designed and synthesized 5 new compounds. Their chemical structures were confirmed by means of MS, HNMR andelemental analysis. FPA was tested for positive inotropic activity. The results showed that FPA could increase the contrastive amplitudeof isolated atrium of guinea pigs and had no influence upon rhythm of the hearts.