用羟基磷灰石和单壁碳纳米管制备葡萄糖传感器的研究

摘要

在滴涂法制得单壁碳纳米管(SWNTs)修饰电极的基础上,采用电化学方法沉积纳米羟基磷灰石(HA)涂层,进而利用分子组装技术将葡萄糖氧化酶(GOD)固定到该电极上,制得的修饰电极的循环伏安测量结果表明,GOD发生了直接的电子传递.GOD-HA-SWNTs/GC修饰电极对不同浓度的葡萄糖呈现两个良好的线性响应范围,有望开发为适合不同用途的新型葡萄糖传感器.%A novel glucose oxidase sensor based on hydroxyapatite (HA) and single-wall carbon nanotube (SWNTs) composite has been developed for the detection of glucose.The hydroxyapatite was electredeposited onto the single-wall carbon nanotubes modified GC electrode.Then the glucose oxidase was immobilized by self-assembled technique with PDDA.The Cyclic voltammetric results of GOD-HA-SWNTs/GC modified electrode showed that the direct electron transfer was occurred.The prepared electrode was applied to determine different concentrations of glucose with differential pulse voltammetry (DPV).The GOD-HA-SWNTs/GC electrode exhibited a good linear response to glucose over two concentration ranges from 0.1 to 2.3mmol/L and 2.3 to 20 mmol/L, respectively.This result is expected to develop a glucose sensor for determine of virious application area.